These Blood Pressure Meds Fight Memory Loss

Almost half of Americans are living with high blood pressure and it is a risk factor for cognitive decline and dementia, along with other diseases.

Almost half of Americans are living with high blood pressure and it is a risk factor for cognitive decline and dementia, along with other diseases.

Two types of blood pressure medications are linked to better memory over time, a review of the research reveals.

Both ACE-inhibitors and angiotensin receptor blockers could reduce the risk of mild cognitive impairment by almost one-fifth.

Mild cognitive impairment, characterised by problems with memory, language and thinking greater than those expected with age, can be a precursor to dementia.

Dr Daniel A. Nation, study co-author, said:

“Research has been mixed on which medicines have the most benefit to cognition.

Studies of angiotensin II receptor blockers and angiotensin-converting-enzyme (ACE) inhibitors have suggested these medicines may confer the greatest benefit to long-term cognition, while other studies have shown the benefits of calcium channel blockers and diuretics on reducing dementia risk.”

The researchers looked at 14 different studies including almost 13,000 people across six countries.

The results showed that the drugs linked to better memory recall crossed the blood-brain barrier.

People in the studies were primarily taking the drugs for high blood pressure.

Almost half of Americans are living with high blood pressure and it is a risk factor for cognitive decline and dementia, along with other diseases.

Dr Nation said:

“Hypertension occurs decades prior to the onset of dementia symptoms, affecting blood flow not only in the body but also to the brain.

Treating hypertension is likely to have long-term beneficial effects on brain health and cognitive function later.”

These are the names of common drugs that do cross the blood-brain barrier that are used to treat hypertension:

  • Angiotensin-converting enzyme inhibitors (ACE inhibitors): enalapril, lisinopril, ramipril, captopril, benazepril.
  • Angiotensin-receptor blocker (ARBs, sartans): valsartan, candesartan, losartan, irbesartan.

Dr Jean K. Ho, the study’s first author, said:

“These findings represent the most powerful evidence to-date linking brain-penetrant ACE-inhibitors and angiotensin receptor blockers to better memory.

It suggests that people who are being treated for hypertension may be protected from cognitive decline if they medications that cross the blood-brain barrier.”

Blood pressure is considered elevated above 120/80 mm/Hg although medication is not normally recommended until the reading is 140/90 mm/Hg.

Between the two readings, people are told to modify their diet and exercise habits.

The study was published in the journal Hypertension (Ho et al., 2021).

This Vitamin Improves Memory And Learning

The right dosage of vitamin supplementation increased memory and learning.

The right dosage of vitamin supplementation increased memory and learning.

Vitamin D supplementation can improve memory, research finds.

Older women who took three times the recommended dose of vitamin D each day showed improvements in memory and learning.

Vitamin D, along with its importance in bone health, is also known to play a role in cognition and the functioning of the nervous system.

While vitamin D may improve memory and learning, the study also linked higher levels of supplements to slower reaction times, which could increase the risk of falls.

The study included overweight and obese older women.

They were split into three groups who each took different doses of vitamin D for one year.

One group took 600 IU per day (the recommended dose — around 15 mcg), another 2,000 IU and a third took 4,000 IU.

Standard cognitive tests were given before and after to test the effect on memory and thinking skills.

The results showed that 600 IU had no effect, but 2,000 IU per day improved memory and learning.

However, the higher dosage also had no effect, suggesting there is a sweet spot for vitamin D supplementation.

The disadvantage of taking too much vitamin D was that it was linked to slower reaction times.

Professor Sue Shapses, study co-author, explained:

“The slower reaction time may have other negative outcomes such as potentially increasing the risk of falling and fractures.

This is possible since other researchers have found that vitamin D supplementation at about 2,000 IU daily or more increased risk of falls, but they did not understand the cause.

Our team’s findings indicating a slower reaction time may be one answer.

Many people think that more vitamin D supplementation is better, but this study shows that is not always the case.”

Professor Shapses thinks that higher doses of vitamin D might not be a problem for younger people.

However, for the elderly it could increase the risk of falls.

Vitamin D is normally obtained through exposure to the sun.

Vitamin D is found in oily fish, egg yolks, fortified cereals and some margarine spreads, among other foods.

The study was published in the Journals of Gerontology: Series A (Castle et al., 2019).

Boost Memory: 10 Psychology Studies To Know

Boosts in all types of memory come from these simple activities.

Boosts in all types of memory come from these simple activities.

1. Draw it

Drawing pictures of words helps build stronger and more reliable memories, research finds.

The quality of the drawings themselves does not matter, the study also found.

This suggests everyone can benefit from the technique, whatever their artistic talent.

2. Close your eyes

Closing your eyes really can help jog the memory, a study finds.

Eyewitness to a crime remembered twice as many details using this technique.

The results should be useful for helping eyewitnesses to crimes remember more details when questioned by police.

3. Imagine how it relates to you

Imagining how things relate to yourself helps to boost recall, psychological research finds.

The study tested people with and without memory problems and found it could help both.

The results showed that whether people had memory problems or not, self-imagining was the most effective strategy.

Compared with the baseline condition, the self-imagining strategy almost tripled what people could remember.

4. 40 seconds rehearsal

Rehearsing a memory for just 40 seconds could be the key to permanent recall, a study finds.

When rehearsing a memory, the same area of the brain is activated as when laying it down, psychologists found.

This brain region — the posterior cingulate — is also the part that is damaged in Alzheimer’s disease.

Brain scans revealed that the more the activity matched when watching and rehearsing, the more people could remember.

5. Run barefoot

Running barefoot improves memory more than running with shoes on, a study finds.

The benefits may come from the extra demands placed on the brain while barefoot running.

For example, you have to avoid stones and anything else that may damage your feet.

The type of memory tested in the study is called ‘working memory’.

The brain uses working memory to recall and process information.

6. Handwrite it

Writing by hand strengthens memory in comparison to writing on a real or virtual keyboard, research finds.

The motor feedback from the process of writing along with the sense of touching paper and pen helps people learn.

Areas of the brain vital to language are more strongly activated by the physical activity.

7. Lift weights

One single workout with weights can immediately enhance long-term memory by around 20%, according to a study.

While it’s now well-established that months of aerobic exercise can enhance memory, this is the first study examining the effects of a relatively short amount of resistance training.

The reason this works is that exercise puts us into a heightened state, after which, memories — especially emotional ones — are more likely to stick.

8, 9 & 10. Childhood activities

Climbing a tree can improve working memory by 50%, a study finds.

The same is true of other dynamic activities like balancing on a beam, carrying awkward weights and navigating around obstacles.

Dr Tracy Alloway, one of the study’s authors, said:

“Improving working memory can have a beneficial effect on so many areas in our life, and it’s exciting to see that proprioceptive activities can enhance it in such a short period of time.”

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Curcumin In Turmeric Boosts Memory May Lower Alzheimer’s Risk

Curcumin, which is found in turmeric, a key ingredient of Indian curries, could explain lower rates of Alzheimer’s in India.

Curcumin, which is found in turmeric, a key ingredient of Indian curries, could explain lower rates of Alzheimer’s in India.

Curcumin — a key ingredient of Indian curries — boosts mood and memory, new research finds.

Curcumin is found in turmeric, which helps give curry its distinctive colour.

Scientists have wondered if curcumin could explain why older people in India — where curcumin is a dietary staple — have lower levels of Alzheimer’s.

Turmeric for memory study

Participants in the study were given a curcumin supplement and followed over 18 months.

The people in the study were all between 50 and 90 years old and all had mild memory problems.

They received either a placebo or 90mg of curcumin twice a day for 18 months.

The results showed that people taking curcumin saw significant improvements in memory (28% better) and attention.

They also felt small improvements in mood.

There were no changes in the placebo group.

Curcumin and Alzheimer’s

Professor Gary Small, the study’s first author, said:

“Exactly how curcumin exerts its effects is not certain, but it may be due to its ability to reduce brain inflammation, which has been linked to both Alzheimer’s disease and major depression.”

Four people in the study suffered side effects of abdominal pain and nausea, although two were taking the placebo in any case.

Professor Small said:

“These results suggest that taking this relatively safe form of curcumin could provide meaningful cognitive benefits over the years.”

The study was published in The American Journal of Geriatric Psychiatry (Small et al., 2017).

How To Boost Long-Term Memory

Long-term memory can be boosted with the easiest method you can imagine.

Long-term memory can be boosted with the easiest method you can imagine.

Simply reading something out loud is the easiest way to boost your long-term memory, research finds.

The action of speaking something out loud and hearing yourself say it helps boost long-term memory.

Psychologists call this ‘the production effect’: we remember things better when we read them out loud than when we read silently to ourselves.

Professor Colin M. MacLeod, who co-authored the study, said:

“This study confirms that learning and memory benefit from active involvement.

When we add an active measure or a production element to a word, that word becomes more distinct in long-term memory, and hence more memorable.”

How to boost long term memory

The study compared various different ways of learning written information and how to boost long term memory:

  1. reading silently,
  2. hearing someone else read it,
  3. listening to a recording of oneself,
  4. reading aloud in real time.

Reading aloud in real-time emerged as the most effective method.

The study’s authors explain that:

“…production is memorable in part because it includes a distinctive, self-referential component.

This may well underlie why rehearsal is so valuable in learning and remembering: We do it ourselves, and we do it in our own voice.

When it comes time to recover the information, we can use this distinctive component to help us to remember.”

Professor MacLeod said:

“When we consider the practical applications of this research, I think of seniors who are advised to do puzzles and crosswords to help strengthen their memory.

This study suggests that the idea of action or activity also improves memory.

And we know that regular exercise and movement are also strong building blocks for a good memory.”

The study’s authors conclude:

“Production is a simple but versatile learning strategy.

[…]

Mouthing, writing, and typing words all have also been revealed to be memory-enhancing productions, and there is evidence that drawing pictures also helps.”

The study was published in the journal Memory (Forrin et al., 2017).

Emotional Hangovers: How One Emotional Experience Influences Subsequent Memories

Emotional events cause neurotransmitters to flood the brain, which affects what we remember.

Emotional events cause neurotransmitters to flood the brain, which affects what we remember.

Emotional experiences can lead to ’emotional hangovers’, research finds.

These ’emotional hangovers’ are still measurable in the brain after the emotional event has finished.

Emotional hangovers can also strongly influence our memory for subsequent events.

Dr Lila Davachi, one of the study’s authors explains:

“How we remember events is not just a consequence of the external world we experience, but is also strongly influenced by our internal states — and these internal states can persist and color future experiences.”

When people have an emotional experience, their memory becomes stronger for non-emotional events that happen afterwards.

In other words, our brain stays on high alert even if subsequent events are not that exciting.

For example, after seeing a particularly emotional movie, we might have a heightened memory for a relatively everyday experience like driving home.

Dr Davachi continued:

” ‘Emotion’ is a state of mind.

These findings make clear that our cognition is highly influenced by preceding experiences and, specifically, that emotional brain states can persist for long periods of time.”

For the research people were shown a series of images, some of which were emotionally arousing.

Brain scans revealed that after viewing arousing images, the brain continues to be in a heightened state of arousal for around 20 to 30 minutes.

The study also found that emotional events release a cocktail of neurotransmitters into the brain.

Dr Davachi said:

“We see that memory for non-emotional experiences is better if they are encountered after an emotional event.”

Previous studies tell us that emotional hangovers also work the other way: like getting the headache before you have a drink.

Emotional events can change our memory for previous events as well, colouring them in different ways.

The study was published in the journal Nature Neuroscience (Tambini et al., 2016).

This Drink Reduces Risk Of Memory Loss 47%

A familiar beverage that may help protect the brain from aging.

A familiar beverage that may help protect the brain from aging.

Orange juice is linked to a 47 percent reduced risk of memory problems with age, a study finds.

People drinking orange juice had a better memory for things like shopping lists and found it easier to follow group conversations, researchers found.

Red vegetables, leafy greens and berry fruits may also help to reduce the risk of memory loss.

The study included 27,842 men who were followed over two decades.

They were asked about their food intake and given tests of thinking and memory at four-yearly intervals.

Questions they were asked included:

  • “Do you have more trouble than usual following a group conversation or a plot in a TV program due to your memory?”
  • “Do you have more trouble than usual remembering a short list of items, such as a shopping list?”

The results showed that those consuming six servings of fruit and vegetables per day were at a 34 percent lower risk of worse thinking skills with age.

Orange juice, meanwhile, was linked to a 47 percent reduced risk.

Eating healthily in midlife emerged as particularly healthy.

Dr Changzheng Yuan, study co-author, said:

“One of the most important factors in this study is that we were able to research and track such a large group of men over a 20-year period of time, allowing for very telling results.

Our studies provide further evidence dietary choices can be important to maintain your brain health.”

The study only shows an association, and does not prove that orange juice causes the reduction in risk.

The study was published in the journal Neurology (Yuan et al., 2018).

Extraordinary Memory At 80: How To Age Gracefully

People who still have an extraordinary memory at 80 reveal how we can all age gracefully.

People who still have an extraordinary memory at 80 reveal how we can all age gracefully.

Warm and trusting social relationships could be the key to having an extraordinary memory when you are 80.

The conclusion comes from research on so-called ‘superagers’ — people who have the cognitive abilities of those up to 30 years younger.

The decline in superager’s memory and other cognitive skills is much slower than their peers, leading to them having extraordinary memories.

They also report having more high-quality and satisfying relationships with other people.

Dr Emily Rogalski, a study author, said:

“You don’t have the be the life of the party, but this study supports the theory that maintaining strong social networks seems to be linked to slower cognitive decline.”

Research on people with an extraordinary memory

The superagers — all over 80 years of age — were asked about six major aspects of psychological well-being:

  • their autonomy,
  • positive relations with others,
  • environmental mastery,
  • personal growth,
  • purpose in life,
  • and self-acceptance.

The real difference between superagers and their peers was in the category of social relations with others.

Ms Amanda Cook, the study’s first author, said:

“This finding is particularly exciting as a step toward understanding what factors underlie the preservation of cognitive ability in advanced age, particularly those that may be modifiable.”

Dr Rogalski said:

“It’s not as simple as saying if you have a strong social network, you’ll never get Alzheimer’s disease.

But if there is a list of healthy choices one can make, such as eating a certain diet and not smoking, maintaining strong social networks may be an important one on that list.

None of these things by themselves guarantees you don’t get the disease, but they may still have health benefits.”

The study on people with an extraordinary memory is part of the Northwestern University SuperAging Program.

The study’s authors explain its aims:

“SuperAgers are adults over age 80 whose performance on tests of episodic memory, the type of memory that shows decline with aging and dramatic decline in Alzheimer’s dementia, is at least as good as individuals 20 to 30 years their junior.

The SuperAging Program is dedicated to identifying factors that contribute to their elite memory performance.

The study was published in the journal PLOS ONE (Maher et al., 2017).

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