Empathy Is Killed By Popular Painkiller Found In 600 Different Drugs

Every week almost one-quarter of Americans use this drug.

Every week almost one-quarter of Americans use this drug.

Acetaminophen — commonly known as Tylenol in the US and paracetamol elsewhere — reduces people’s empathy for the pain of others, new research finds.

Acetaminophen is an ingredient in over 600 different medications, including being the main constituent of Tylenol.

The ubiquitous painkiller does not just kill pain, it also kills our fellow-feeling.

Dr Dominik Mischkowski, the study’s first author, said:

“These findings suggest other people’s pain doesn’t seem as big of a deal to you when you’ve taken acetaminophen.

Acetaminophen can reduce empathy as well as serve as a painkiller.”

Previous research has also found that the drug can reduce the positive emotions of those taking it.

Dr Baldwin Way, a study co-author, said:

“We don’t know why acetaminophen is having these effects, but it is concerning.

Empathy is important.

If you are having an argument with your spouse and you just took acetaminophen, this research suggests you might be less understanding of what you did to hurt your spouse’s feelings.”

The research was carried out on 80 college students.

Half were given a dose of 1,000mg of acetaminophen and the other half a placebo.

They then read a series of stories about people who had been hurt and were asked to rate their pain.

The results showed that those who had taken the acetaminophen consistently gave lower pain ratings for the people in the story.

The researchers carried out a couple of other variations to test people’s’ empathy for physical and social pain.

Dr Way explained the results of the experiment on social pain:

“In this case, the participants had the chance to empathize with the suffering of someone who they thought was going through a socially painful experience.

Still, those who took acetaminophen showed a reduction in empathy.

They weren’t as concerned about the rejected person’s hurt feelings.”

The researchers are now moving on to ibuprofen to see if the findings are the same.

The study was published in the journal Social Cognitive and Affective Neuroscience (Mischkowski et al., 2016).


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It’s mostly written by psychologist and author, Dr Jeremy Dean.

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Author: Jeremy Dean

Psychologist, Jeremy Dean, PhD is the founder and author of PsyBlog. He holds a doctorate in psychology from University College London and two other advanced degrees in psychology. He has been writing about scientific research on PsyBlog since 2004. He is also the author of the book "Making Habits, Breaking Habits" (Da Capo, 2013) and several ebooks.